Endocrine Abstracts

Exposure to maternal obesity or overfeeding during early development has lasting effects upon the young adult rat. Maternal cafeteria (CD) feeding during lactation programmes behaviour in the adult offspring, reducing anxiety in males and altering the behavioural satiety sequence in females. The aim of the present study was to examine the impact of early exposure to maternal over-nutrition upon bioactive amines in the brain. Lactating Wistar rats were fed either a control chow...

A 57 year-old gentleman with uncomplicated Type 2 Diabetes Mellitus and 30 pack year smoking history was assessed in outpatient endocrinology clinic with a 4 month history of non-specific symptoms, including dizziness, lack of energy and intermittent bi-frontal headaches described as ‘pressure behind the eyes’. There was no history of exogenous steroid use. Bloods at 0833 h identified deficiency in testosterone (<1 nmol/l; N= 6–30 nmol/l), thyroxine...